Article

DNA sequencing and gene-expression profiling assists in making a tissue of origin diagnosis in cancer of unknown primary

2022-06-27

Abstract excerpt

Cancer of unknown primary (CUP) constitutes a group of metastatic cancers in which standardized clinical investigations fail to identify a tissue of origin (TOO). Gene-expression profiling (GEP) has been used to resolve TOO, and DNA sequencing to identify potential targeted treatments; however, these methods have not been widely applied together in CUP patients. To assess the diagnostic utility of DNA and RNA test...

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Literature Corpus work: 9fdcab8d-cfea-51eb-80af-72ae32eff081
DOI: 10.1101/2022.06.24.22276729

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