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<i>HLA-B27</i> and not variation in <i>MICA</i> is responsible for genotype by sex interaction in risk of Ankylosing Spondylitis

2021-12-17

Abstract excerpt

Ankylosing Spondylitis (AS) is a highly heritable inflammatory arthritis which occurs more frequently in men than women. In their recent publication examining sex differences in the genetic aetiology of common complex traits and diseases, Bernabeu et al. (2021) observe differences in heritability of AS between sexes, and a genome-wide significant genotype by sex interaction in risk of AS at the major histocompatab...

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Literature Corpus work
9fd21293-e75b-50e1-9107-296b6d96afd8
DOI
10.1101/2021.12.16.21267808
Open publication

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