Article
Investigating the causal relationship between immune factors and ankylosing spondylitis: insights from a Mendelian Randomization study.
Advances in rheumatology (London, England) - 18 Dec 2024
Geng Ziming, Tong Yang, Chen Yang, Wang Jian, Liu Ziwen, Miao Jun, Li Ruihua
Abstract excerpt
BACKGROUND: Despite previous studies indicating a close relationship between immune system and ankylosing spondylitis (AS), the causal relationship between them remains unclear. METHODS: Genome-wide association data were utilized to explore the causal link between 731 immune cells and AS using a bidirectional two-sample MR approach. The data included immune cell data from Orrù et al.'s study and AS data from the...
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