Article

Discovery and characterization of a lactonase in gut microbiota that initiates the metabolism of ellagic acid

2025-12-07

Abstract excerpt

Ellagic acid (EA), a natural plant polyphenol, and its metabolite urolithin (Uro) exhibit significant bioactivity, with Uro being recognized as the active compound responsible for the in vivo effects of EA. Although specific intestinal microorganisms that can metabolize EA have been discovered, the corresponding biochemical routes and genetic mechanisms involved in these processes have yet to be fully elucidated....

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Literature Corpus work: 28c13969-f1b4-5ec6-9e1d-28a80359a77a
DOI: 10.64898/2025.12.05.692447

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