Article

The presence and induction of regioselective dehydroxylases dictate urolithin metabolism by <i>Enterocloster</i> species

2025-08-06

Abstract excerpt

Urolithins are a class of bioactive metabolites derived from the metabolism of dietary ellagitannins by the human gut microbiota. In the gut, urolithins are dehydroxylated regioselectively based on microbiota composition and activity. A single 9-hydroxy urolithin dehydroxylase ( ucd ) operon in gut resident Enterocloster species has been described to date; however, most enzymes in the urolithin metabolic pathway...

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Literature Corpus work: 016a8da5-3062-55a7-ad1a-b1b01e505ae1
DOI: 10.1101/2025.08.06.668933

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