Article

Dissecting <i>ARL15</i> Function in Rheumatoid Arthritis: Insights from <i>Ex Vivo</i> and <i>In Vitro</i> Synovial Fibroblast Models

2025-07-04

Abstract excerpt

ARL15 , coding for a small GTPase was identified as a non-HLA susceptibility gene in rheumatoid arthritis (RA) through a GWAS in a North Indian cohort. Serum adiponectin and ARL15 levels were higher in RA patients with the associated genotype. The present study aimed to delineate the functional role of ARL15 in RA pathobiology using gene knockdown (KD) combined with transcriptomic profiling in both ex-vivo RA sy...

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Literature Corpus work: 9f843108-eedd-59c5-baa6-a0dea0e6bf8e
DOI: 10.1101/2025.06.30.662131

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Dissecting <i>ARL15</i> Function in Rheumatoid Arthritis: Insights from <i>Ex Vivo</i> and <i>In Vitro</i> Synovial Fibroblast ModelsDOI 10.1101/2025.06.30.662131Read

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