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CD5L insufficiency exacerbates skeletal joint damage in rheumatoid arthritis

2025-12-18

Abstract excerpt

CD5L is an immunoregulatory protein induced during inflammation and makes a life-saving contribution in infection and sepsis. Here, we explored the overall impact of CD5L in rheumatoid arthritis (RA). Using experimental RA models, we demonstrated an early surge of CD5L expression in wild-type mice, as well as a higher incidence and increased severity of arthritis in CD5L-deficient mice. In the blood, CD5L-deficien...

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Identifiers and source

Literature Corpus work
89eb0977-8360-5abe-97c5-c30b9bf048eb
DOI
10.64898/2025.12.16.694616
Open publication

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CD5L insufficiency exacerbates skeletal joint damage in rheumatoid arthritisDOI 10.64898/2025.12.16.694616
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