Article

<i>ARL15</i> promotes inflammatory fibroblast activation and disease severity in rheumatoid arthritis: integrated transcriptomic and collagen-induced arthritis model analyses

2026-07-01

Abstract excerpt

<h4>Background</h4> ADP-ribosylation factor-like protein 15 ( ARL15 ) is a rheumatoid arthritis (RA) susceptibility gene identified through GWAS. Previous studies suggested a role for ARL15 in synovial fibroblast (SF) pathogenicity, but its contribution to inflammatory arthritis remains unclear. We investigated the inflammatory role of ARL15 and its therapeutic potential in RA. <h4>Methods</h4> ARL15 was overe...

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Literature Corpus work: 65175f25-c4ad-50c9-89cd-7048378cad59
DOI: 10.64898/2026.06.26.733622

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