Article

Computational analyses of small molecules activity from phenotypic screens

2019-01-01

Abstract excerpt

Drug discovery is no longer relying on the one gene-one disease paradigm nor on target-based screening alone to discover new drugs. Phenotypic-based screening is regaining momentum to discover new compounds since those assays provide an environment closer to the physiological state of the disease and allow to better anticipate off-target effects and other factors that can limit the efficacy of the drugs. However,...

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Literature Corpus work: 9f765a20-329b-58f6-b62c-4f7c19d5c57c
DOI: 10.17863/cam.40403

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