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Article

Chemoproteomic-enabled phenotypic screening.

Cell chemical biology - 18 Mar 2021

Conway Louis P, Li Weichao, Parker Christopher G

Abstract excerpt

The ID of disease-modifying, chemically accessible targets remains a central priority of modern therapeutic discovery. The phenotypic screening of small-molecule libraries not only represents an attractive approach to identify compounds that may serve as drug leads but also serves as an opportunity to uncover compounds with novel mechanisms of action (MoAs). However, a major bottleneck of phenotypic screens...

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Identifiers

PMID: 33577749
DOI: 10.1016/j.chembiol.2021.01.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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