Article

Colchicine attenuates a macrophage inflammatory-proteolytic program associated with carotid plaque vulnerability

2026-06-09

Abstract excerpt

<title>Abstract</title> <p>Background Low-dose colchicine reduces recurrent vascular events, but the plaque-level programs most closely aligned with its vascular pharmacology remain incompletely defined. We aimed to identify a reproducible and experimentally tractable inflammatory-proteolytic program associated with carotid plaque vulnerability. Methods We integrated public bulk transcriptomic prioritization, d...

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Literature Corpus work: 9ef972db-6a69-5ed5-83b1-3fd2791b6fca
DOI: 10.21203/rs.3.rs-9948532/v1

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