Article
Chitinase 3 like 1 is a regulator of smooth muscle cell physiology and atherosclerotic lesion stability.
Cardiovascular research - 17 Dec 2021
Tsantilas Pavlos, Lao Shen, Wu Zhiyuan, Eberhard Anne, Winski Greg, Vaerst Monika, Nanda Vivek, Wang Ying, Kojima Yoko, Ye Jianqin, Flores Alyssa, Jarr Kai-Uwe, Pelisek Jaroslav, Eckstein Hans-Henning, Matic Ljubica, Hedin Ulf, Tsao Philip S, Paloschi Valentina, Maegdefessel Lars, Leeper Nicholas J
Abstract excerpt
AIMS: Atherosclerotic cerebrovascular disease underlies the majority of ischaemic strokes and is a major cause of death and disability. While plaque burden is a predictor of adverse outcomes, plaque vulnerability is increasingly recognized as a driver of lesion rupture and risk for clinical events. Defining the molecular regulators of carotid instability could inform the development of new biomarkers and/or...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.