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Unveiling Anti-atherosclerotic Targets of Perilla frutescens through a Multi-scale Computational Framework Integrating Network Pharmacology, Single-cell Analysis, Machine Learning, and Molecular Dynamics

2026-04-16

Abstract excerpt

<title>Abstract</title> <p> Despite the widespread implementation of lipid-lowering therapy, the persistence of residual inflammatory risk, driven by immunometabolic network dysregulation, remains a cardinal therapeutic challenge in atherosclerosis (AS) management. While <italic>Perilla frutescens</italic> exhibits well-documented anti-inflammatory properties, the precise molecular targeting within the atheros...

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Literature Corpus work
b3bfbdf3-5eeb-519e-be58-486c47ae2644
DOI
10.21203/rs.3.rs-9174552/v1
Open publication

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Unveiling Anti-atherosclerotic Targets of Perilla frutescens through a Multi-scale Computational Framework Integrating Network Pharmacology, Single-cell Analysis, Machine Learning, and Molecular DynamicsDOI 10.21203/rs.3.rs-9174552/v1
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