Article

Early immune pressure imposed by tissue resident memory T cells sculpts tumour evolution in non-small cell lung cancer

2021-04-20

Abstract excerpt

<title>Abstract</title> <p>Tissue-resident memory T cells (TRM) provide immune defence against local infection and can inhibit cancer progression. However, it is unclear to what extent chronic inflammation impacts TRM activation and how the immune pressure exerted by TRM affects developing tumours in humans. We performed deep profiling of lung cancers arising in never-smokers (NS) and ever-smokers (ES), finding e...

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Literature Corpus work: 9ef41f37-c1a1-5357-a749-eac8bd0b120a
DOI: 10.21203/rs.3.rs-432815/v1

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