Article

Gene expression analysis suggests immunosuppressive roles of endolysosomes in glioblastoma

2023-09-01

Abstract excerpt

Targeting endolysosomes is a strategy extensively pursued for treating cancers, including glioblastomas (GBMs), mainly on the basis that the intact function of these subcellular organelles is key to tumor cell autophagy and survival. Here, by gene expression analyses and cell type abundance estimation in GBMs, we showed that genes associated with the endolysosomal machinery are more prominently featured in non-tum...

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Literature Corpus work: 9edf5fd6-3f5d-5005-8fc5-02b2b84435b8
DOI: 10.1101/2023.08.31.555740

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