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Novel macrophage-related gene prognostic index for glioblastoma associated with M2 macrophages and T cell dysfunction

13 Sept 2022

Abstract excerpt

This study aims to construct a Macrophage-Related Gene Prognostic Index (MRGPI) for glioblastoma (GBM) and explore the underlying molecular, metabolic, and immunological features. Based on the GBM dataset from The Cancer Genome Atlas (n = 156), 13 macrophage-related hub genes were identified by weighted gene co-expression network (WGCNA) analysis. 5 prognostic genes screened by Kaplan-Meire (K-M) analysis and Cox...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36177003
DOI: 10.3389/fimmu.2022.941556

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