Article

The m 6 A methyltransferase METTL3 affects cell proliferation and migration by regulating YAP expression in Hirschsprung disease

2022-12-05

Abstract excerpt

<h4>Background: </h4> METTL3, a mRNA m 6 A methyltransferase, has been implicated in various steps of mRNA metabolism, such as stabilization, splicing, nuclear transportation, translation, and degradation. However, whether METTL3 dysregulation is involved in Hirschsprung disease (HSCR) development remains unclear. In this study, we preliminarily elucidated the role of METTL3 in HSCR and sought to identify the asso...

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Literature Corpus work: 9edb5d0a-053e-5aa6-b638-bcbe6deeb565
DOI: 10.21203/rs.3.rs-2323729/v1

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