Article

METTL3 facilitates hepatic fibrosis progression via m <sup>6</sup> A-YTHDF2 dependent silencing of GPR161

2021-12-15

Abstract excerpt

Hepatic fibrosis (HF) is a very common condition seen in millions of patients with various liver diseases. N 6 -methyladenosine (m 6 A) plays critical roles in various biological and pathological processes. However, the role of m 6 A and its main methyltransferase METTL3 in HF remains obscure. Here, we reported that METTL3 expression was elevated in HSCs from CCl4 induced fibrotic liver. METTL3 knockdown in HSC...

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Literature Corpus work: bd8e1d2e-fb27-585b-bff8-4dd2c1adca87
DOI: 10.1101/2021.12.15.472749

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METTL3 facilitates hepatic fibrosis progression via m <sup>6</sup> A-YTHDF2 dependent silencing of GPR161DOI 10.1101/2021.12.15.472749Read

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