Article

<i>N</i> <sup>6</sup> -methyladenosine promotes temozolomide resistance through mRNA stabilization in glioblastoma cells

2025-09-15

Abstract excerpt

<h4>ABSTRACT</h4> N 6 -methyladenosine (m 6 A) is a critical regulator of mRNA processing and function, impacting nearly every step of the mRNA lifecycle. Changes in m 6 A status have been implicated in many different types of cancer, including glioblastoma where acquired resistance to temozolomide remains a major clinical challenge. We established glioblastoma cell culture models of acquired temozolomide resis...

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Literature Corpus work: 6ce745b9-0177-5037-8f41-18330f78b278
DOI: 10.1101/2025.09.14.676126

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