Article

TCF4 and HuR Mediated-METTL14 Suppresses Dissemination of Colorectal Cancer via N6-Methyladenosine-Dependent Silencing of ARRDC4

2021-07-07

Abstract excerpt

<h4>Background: </h4> Metastasis remains the major obstacle to improved survival for colorectal cancer (CRC) patients. Dysregulation of N6-methyladenosine (m6A) is causally associated with the development of metastasis through poorly understood mechanisms. <h4>Methods: </h4>: The expression of METTL14 and its correlation with clinicopathological features were evaluated by western blot and immunohistochemistry. The...

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Literature Corpus work: f1225004-b01d-5a57-9bed-8b35b6ec4086
DOI: 10.21203/rs.3.rs-648817/v1

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