Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

METTL3 regulates N6-methyladenosine modification of ANGPTL3 mRNA and potentiates malignant progression of stomach adenocarcinoma

21 Jun 2023

Abstract excerpt

BACKGROUND: N6-methyladenosine (m6A) is associated with mammalian mRNA biogenesis, decay, translation and metabolism, and also contributes greatly to gastrointestinal tumor formation and development. Therefore, the specific mechanisms and signaling pathways mediated by methyltransferase-like 3 (METTL3), which catalyzes the formation of m6A chemical labeling in stomach adenocarcinoma (STAD), are still worth...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related gene regulation
Share to Lipid metabolism and disorders
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37344779
DOI: 10.1186/s12876-023-02844-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

METTL3 regulates N6-methyladenosine modification of ANGPTL3 mRNA and potentiates malignant progression of stomach adenocarcinomaPMID 37344779Read ↗

N 6 -methyladenosine (m 6 A) RNA methylation signature as a predictor of stomach adenocarcinoma outcomes and its association with immune checkpoint moleculesSemantic proximity Read ↗

METTL14-dependent m 6 A modification of circUGGT2 drives gastric cancer progression by sponging miR-186-3p and upregulating MAP3K9Semantic proximity Read ↗

The m6A demethylase FTO promotes esophageal cancer progression via the YTHDF1/AKT3 signaling networkSemantic proximity Read ↗

The m6A demethylase FTO promotes esophageal cancer progression through YTHDF1-dependent posttranscriptional silencing of AKT3Semantic proximity Read ↗

A cancer-associated METTL14 mutation induces aberrant m6A modification, affecting tumor growth.Semantic proximity Read ↗

N6-methyladenosine demethylase FTO promotes growth and metastasis of gastric cancer via m6A modification of caveolin-1 and metabolic regulation of mitochondrial dynamicsSemantic proximity Read ↗

METTL3 promotes lung adenocarcinoma tumor growth and inhibits ferroptosis by stabilizing SLC7A11 m6A modificationSemantic proximity Read ↗

Multimodal tumor suppression by METTL3 gene knockdown in melanoma and colon cancer cellsSemantic proximity Read ↗

Cancer mutations rewire the RNA methylation specificity of METTL3-METTL14Semantic proximity Read ↗

The M6A Methyltransferase METTL3 drives thyroid cancer progression and lymph node metastasis by targeting LINC00894Semantic proximity Read ↗

Epigenetic Regulation of m6A Modifications in Human CancerSemantic proximity Read ↗

The m 6 A methyltransferase METTL3 affects cell proliferation and migration by regulating YAP expression in Hirschsprung diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.