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Attenuation of mosaic aneuploidy and erroneous first mitotic division of human embryos

2025-04-06

Abstract excerpt

Human reproduction is inherently inefficient 1 and 1 in 6 people worldwide suffer infertility. In vitro fertilisation (IVF) can help some couples conceive, but only ~30% of cycles are successful. One factor affecting IVF efficacy is mitotic-origin (mosaic) aneuploidy in which embryos contain a mixture of cells with different numbers of chromosomes 2 . We previously showed that chromosome segregation error phenot...

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Literature Corpus work
9eab114a-3f33-5960-b2c7-80242d389742
DOI
10.1101/2025.04.05.647367
Open publication

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Attenuation of mosaic aneuploidy and erroneous first mitotic division of human embryosDOI 10.1101/2025.04.05.647367
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