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On the origin of mitosis-derived human embryo aneuploidy

29 Nov 2024

Abstract excerpt

Chromosome segregation errors are common in the early stages of human embryonic development. By examining the first mitotic divisions of human embryos using live cell imaging, three recent studies identify spindle architecture and positioning features that could provide insights into why early embryos are predisposed to chromosomal abnormalities.

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PMID: 39613785
DOI: 10.1038/s41467-024-54953-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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