Article

Histone H4K20 Trimethylation is Decreased in Murine Models of Heart Disease

2022-02-10

Abstract excerpt

<h4>ABSTRACT</h4> Heart disease is the leading cause of death in the developed world, and its comorbidities such as hypertension, diabetes, and heart failure are accompanied by major transcriptomic changes in the heart. During cardiac dysfunction, which leads to heart failure, there are global epigenetic alterations to chromatin that occur concomitantly with morphological changes in the heart in response to acute...

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Literature Corpus work: 9e994a3b-3a85-51df-a602-f2c952b8eab4
DOI: 10.1101/2022.02.10.479885

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