Roles of histone acetylation sites in cardiac hypertrophy and heart failure

Abstract excerpt

Heart failure results from various physiological and pathological stimuli that lead to cardiac hypertrophy. This pathological process is common in several cardiovascular diseases and ultimately leads to heart failure. The development of cardiac hypertrophy and heart failure involves reprogramming of gene expression, a process that is highly dependent on epigenetic regulation. Histone acetylation is dynamically...

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• Histone Deacetylase Inhibitors Research
• Peptidase Inhibition and Analysis
• Signaling Pathways in Disease