Article

Localization of regions of a <i>Bordetella pertussis</i> autotransporter, Vag8, interacting with C1 inhibitor

2020-03-09

Abstract excerpt

Bordetella pertussis is the causative agent of pertussis (whooping cough), a contagious respiratory disease that has recently seen a resurgence despite high vaccination coverage, necessitating improvement of current pertussis vaccines. An autotransporter of B. pertussis , virulence-associated gene 8 (Vag8), has been proposed as an additional component to improve pertussis vaccines. Vag8 is known to play a role in...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ab15bb93-1df1-5d18-a063-a682a8a4ffce
DOI: 10.1101/2020.03.09.983296

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Localization of regions of a <i>Bordetella pertussis</i> autotransporter, Vag8, interacting with C1 inhibitorDOI 10.1101/2020.03.09.983296Read

Molecular basis for <i>B. pertussis</i> interference with complement, coagulation, fibrinolytic and contact activation systems: The cryo-EM structure of the Vag8-C1 inhibitor complexSemantic proximity Read

Acquisition of C1 inhibitor by Bordetella pertussis virulence associated gene 8 results in C2 and C4 consumption away from the bacterial surfaceSemantic proximity Read

Bordetella pertussis autotransporter Vag8 binds human C1 esterase inhibitor and confers serum resistance.Semantic proximity Read

Molecular Basis for Bordetella pertussis Interference with Complement, Coagulation, Fibrinolytic, and Contact Activation Systems: the Cryo-EM Structure of the Vag8-C1 Inhibitor Complex.Semantic proximity Read

A dual role for PGLYRP1 in host defense and immune regulation during <i>B. pertussis</i> infectionSemantic proximity Read

Pertussis: a matter of immune modulationSemantic proximity Read

Complement evasion by Bordetella pertussis: implications for improving current vaccinesSemantic proximity Read

Contribution of pertussis toxin to the pathogenesis of pertussis disease: Graphical Abstract Figure.Semantic proximity Read

Pertussis: Microbiology, Disease, Treatment, and PreventionSemantic proximity Read

<em>Bordetella pertussis</em> Infection: From Immune Pathogenesis to Next-Generation VaccinesSemantic proximity Read

Bps polysaccharide of <i>Bordetella pertussis</i> resists antimicrobial peptides by functioning as a dual surface shield and decoy and converts <i>Escherichia coli</i> into a respiratory pathogenSemantic proximity Read

Bordetella pertussis pathogenesis: current and future challengesSemantic proximity Read