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Bps polysaccharide of <i>Bordetella pertussis</i> resists antimicrobial peptides by functioning as a dual surface shield and decoy and converts <i>Escherichia coli</i> into a respiratory pathogen

2022-04-06

Abstract excerpt

Infections and disease caused by the obligate human pathogen Bordetella pertussis (Bp) are increasing, despite widespread vaccinations. The current acellular pertussis vaccines remain ineffective against nasopharyngeal colonization, carriage, and transmission. In this work, we tested the hypothesis that Bordetella polysaccharide (Bps), a member of the poly-β-1,6- A -acetyl-D-glucosamine (PNAG/PGA) family of poly...

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Literature Corpus work
bc956b73-25df-5911-a678-8a7291550159
DOI
10.1101/2022.04.06.487353
Open publication

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Bps polysaccharide of <i>Bordetella pertussis</i> resists antimicrobial peptides by functioning as a dual surface shield and decoy and converts <i>Escherichia coli</i> into a respiratory pathogenDOI 10.1101/2022.04.06.487353
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