Article

miRNA-92a Inhibits the Phenotypic Modulation of Vascular Smooth Muscle Cells and May Help to Prevent In-Stent Restenosis

2022-03-07

Abstract excerpt

The modulation of the phenotype of vascular smooth muscle cells (VSMCs) during cell proliferation and migration may represent a potential therapeutic approach for the prevention of vascular intimal hyperplasia. However, the precise role of this process in the biology and remodeling of VSMCs remains unclear. Herein, we demonstrate that miR-92a modulates VSMCs to a synthetic phenotype via the KLF4 pathway. Targeting...

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Literature Corpus work: 9e0ead02-b574-5aa4-a3df-c53770c98a5a
DOI: 10.21203/rs.3.rs-1085399/v1

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