Article

Distinct Co-Methylation Patterns in African and European Populations and Their Genetic Associations

2025-03-17

Abstract excerpt

Human populations have substantial genetic diversity, but the extent of epigenetic diversity remains unclear, as population-specific DNA methylation (DNAm) has only been studied for ∼3.0% of CpGs. This study quantifies DNAm using whole-genome bisulfite sequencing (WGBS) and analyzes it alongside whole-genome genotype data to reveal a comprehensive picture of population-specific DNAm. Using a “co-methylated region”...

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Literature Corpus work: 9df2c01a-1dc3-5490-975b-30146b8c20e0
DOI: 10.1101/2025.03.16.643544

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