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Spatial dynamics of IFITM1: a core component of the interferon-stimulated gene-resistance signature in glioma

2025-07-16

Abstract excerpt

The IFITM1 protein is a key component of the Interferon-Stimulated Gene (ISG) network, which has been linked to treatment-resistant signatures in various cancers, including glioblastoma (GBM). Despite its impact, the mechanisms underlying IFITM1’s role in cancer remain poorly understood. Here, we demonstrate that the spatial dynamics of IFITM1 localisation are highly context-dependent, particularly in GBM tissue....

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Identifiers and source

Literature Corpus work
9defafe5-1686-5c7e-8778-3828cc16efd6
DOI
10.1101/2025.07.16.661931
Open publication

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Spatial dynamics of IFITM1: a core component of the interferon-stimulated gene-resistance signature in gliomaDOI 10.1101/2025.07.16.661931
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