Article

The Autoimmune Susceptibility Gene, <i>PTPN2</i> , Restricts Expansion of a Novel Mouse Adherent-Invasive <i>E. coli</i>

2019-07-22

Abstract excerpt

Inflammatory bowel diseases (IBD) involve genetic and environmental factors that play major roles in disease pathogenesis. Loss-of-function single-nucleotide polymorphisms (SNPs) in the protein tyrosine phosphatase non-receptor type 2 ( PTPN2 ) gene increase the risk of IBD and are associated with altered microbiome population dynamics in IBD. Moreover, expansion of intestinal pathobionts, such as adherent-invasi...

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Literature Corpus work: 9dd0d804-4ac2-5116-829e-d6126d598dff
DOI: 10.1101/709634

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