Article

Immune phenotype-guided identification of disease-associated pathobionts in Crohn’s disease

2025-04-07

Abstract excerpt

<h4>Summary</h4> Aberrant immune activation within the gut mucosa and gut dysbiosis have been implicated in the pathogenesis of Crohn’s disease (CD). However, the specific immune responses triggered by dysbiotic microbiota, as well as the bacteria responsible for this activation, remain incompletely understood. Here, using the human microbiota-associated (HMA) mouse system, we demonstrated that colonization with...

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Literature Corpus work: db403d33-55e8-52c7-b911-7fbb4033c8fc
DOI: 10.1101/2025.04.01.646605

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