Article

Quick and robust method for the generation of human iPSC-derived choroid plexus organoids

2025-08-21

Abstract excerpt

The choroid plexus (ChP) is a key brain structure responsible for cerebrospinal fluid (CSF) production and forms a selective barrier that regulates brain homeostasis and immune surveillance. In vitro models of ChP are essential for studying CSF dynamics, viral entry, neuroinflammation, and CNS drug transport, yet current organoid protocols remain complex, slow, and difficult to reproduce. Here, we report a quick a...

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Identifiers and source

Literature Corpus work: ee93e7f6-cb15-5716-8ede-856b92a43155
DOI: 10.1101/2025.08.20.671243

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