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Article

Modeling neurological disorders using brain organoids.

Seminars in cell & developmental biology - 1 Mar 2021

Zhang Daniel Y, Song Hongjun, Ming Guo-Li

Abstract excerpt

Neurological disorders are challenging to study given the complexity and species-specific features of the organ system. Brain organoids are three dimensional structured aggregates of neural tissue that are generated by self-organization and differentiation from pluripotent stem cells under optimized culture conditions. These brain organoids exhibit similar features of structural organization and cell type...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32561297
DOI: 10.1016/j.semcdb.2020.05.026
PMCID: PMC7738381

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