Article

Nonstructural protein 1 of SARS-CoV-2 is a potent pathogenicity factor redirecting host protein synthesis machinery toward viral RNA

2020-08-10

Abstract excerpt

<h4>Summary</h4> The COVID-19 pandemic affects millions of people worldwide with a rising death toll. The causative agent, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), uses its nonstructural protein 1 (Nsp1) to redirect host translation machinery to the viral RNA by binding to the ribosome and suppressing cellular, but not viral, protein synthesis through yet unknown mechanisms. We show here that...

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Literature Corpus work: 9d208bdd-1c30-5a7e-839d-85c8e4dd40c6
DOI: 10.1101/2020.08.09.243451

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