Article

Parsing the role of NSP1 in SARS-CoV-2 infection

2022-03-14

Abstract excerpt

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the ongoing coronavirus disease 19 (COVID-19) pandemic. Despite its urgency, we still do not fully understand the molecular basis of SARS-CoV-2 pathogenesis and its ability to antagonize innate immune responses. SARS-CoV-2 leads to shutoff of cellular protein synthesis and over-expression of nsp1, a central shutoff factor in coronaviruses...

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Literature Corpus work: 1987aa93-e047-57c1-9d66-93c3a27bb98c
DOI: 10.1101/2022.03.14.484208

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