Article
Conserved Human CpG Dinucleotides Identify Enriched Ageing-related Signals in Developmental Pathways and the Brain
2026-02-20
Abstract excerpt
The DNA methylome changes with age. This is observed as both random drift, but also consistent alterations within certain genomic loci enabling the construction of precise age predictors. However, the functionality of these ageing-related modifications remains largely undefined. The CpG dinucleotide is the principal sequence target for these epigenetic DNA marks in differentiated cells. Here, for functional insigh...
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Identifiers and source
- Literature Corpus work
- 9cb8456d-8324-5e38-bca2-8a04b7f1d6f7
- DOI
- 10.64898/2026.02.20.707043