Article
Dynamic methylome modification is associated with mutational signatures in aging and the etiology of disease
2020-12-22
Abstract excerpt
Reversible epigenetic changes within the loci of genes that regulate critical cell processes have recently emerged as important biomarkers of disease pathology. It is then natural to consider the consequences for population health risk of such epigenetic changes during the aging process. Specifically, the interplay between dynamic methylation changes that accompany aging and mutations that accrue in an individual’...
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Identifiers and source
- Literature Corpus work
- ed39a5c7-ef37-5c98-9f0c-19cd52f2a917
- DOI
- 10.1101/2020.12.22.423778
