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Article

Dynamic methylome modification is associated with mutational signatures in aging and the etiology of disease

2020-12-22

Abstract excerpt

Reversible epigenetic changes within the loci of genes that regulate critical cell processes have recently emerged as important biomarkers of disease pathology. It is then natural to consider the consequences for population health risk of such epigenetic changes during the aging process. Specifically, the interplay between dynamic methylation changes that accompany aging and mutations that accrue in an individual’...

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Literature Corpus work
ed39a5c7-ef37-5c98-9f0c-19cd52f2a917
DOI
10.1101/2020.12.22.423778
Open publication

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Dynamic methylome modification is associated with mutational signatures in aging and the etiology of diseaseDOI 10.1101/2020.12.22.423778
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