Article

Identification of non-canonical peptides with moPepGen

2024-03-31

Abstract excerpt

Proteogenomics is limited by challenges of modeling the complexities of gene expression. We create moPepGen, a graph-based algorithm that comprehensively generates non-canonical peptides in linear time. moPepGen works with multiple technologies, in multiple species and on all types of genetic and transcriptomic data. In human cancer proteomes, it enumerates previously unobservable noncanonical peptides arising fro...

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Literature Corpus work: 9c9c9d06-9d1a-545b-a9ec-7909bd5a8512
DOI: 10.1101/2024.03.28.587261

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