Article

The Prevalence of <i>pks<sup>+</sup> E. coli </i>in Cystic Fibrosis

2025-02-13

Abstract excerpt

Cystic fibrosis (CF) patients experience higher risks of colorectal cancer, but pathogenesis is unclear. In the general population, polyketide synthase-positive (pks+) E. coli is impli-cated in intestinal carcinogenesis via production of colibactin, however relevance in CF is unknown. We investigated pks+ E. coli prevalence in CF at baseline and longitudinally, performing PCR on stool DNA extracts. Potential assoc...

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Literature Corpus work: 9c903f74-c40a-5835-9564-1c5a0368891d
DOI: 10.20944/preprints202502.0874.v1

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