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The Fra-1: Novel role in regulating extensive immune cell states and affecting inflammatory diseases

11 Aug 2022

Abstract excerpt

Fra-1(Fos-related antigen1), a member of transcription factor activator protein (AP-1), plays an important role in cell proliferation, apoptosis, differentiation, inflammation, oncogenesis and tumor metastasis. Accumulating evidence suggest that the malignancy and invasive ability of tumors can be significantly changed by directly targeting Fra-1. Besides, the effects of Fra-1 are gradually revealed in immune and...

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Cell death mechanisms and regulation
Cytokine Signaling Pathways and Interactions
NF-κB Signaling Pathways

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 36032067
DOI: 10.3389/fimmu.2022.954744

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