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HIC1 interacts with FOXP3 multi protein complex: a novel mechanism to regulate human regulatory T cell differentiation and function

2023-05-15

Abstract excerpt

Transcriptional repressor, hypermethylated in cancer 1 (HIC1) participates in a range of important biological processes, such as tumor repression, immune suppression, embryonic development and epigenetic gene regulation. Further to these, we previously demonstrated that HIC1 provides a significant contribution to the function and development of regulatory T (Treg) cells. However, the mechanism by which it regulate...

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Literature Corpus work
50b09312-7694-5a9f-9327-c9a02bdf31eb
DOI
10.1101/2023.05.15.540505
Open publication

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HIC1 interacts with FOXP3 multi protein complex: a novel mechanism to regulate human regulatory T cell differentiation and functionDOI 10.1101/2023.05.15.540505
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