Article

<i>Bax-inhibitor-1</i> loss of function phenotypes are suppressed by <i>Buffy</i> in <i>Drosophila</i>

2016-10-24

Abstract excerpt

<h4>Background: </h4> Bax Inhibitor-1 (BI-1), an integral transmembrane protein, acts as a suppressor of Bax -induced apoptosis through regulation of endoplasmic reticulum (ER) stress-induced cell death. The gene is highly conserved being found in a diverse range of organisms that include yeast, Arabidopsis, Drosophila, mouse and humans. BI-1 is implicated in the regulation of calcium levels, reactive oxygen spec...

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Literature Corpus work: 9c64c378-ecf7-5c56-a6ee-075dd4c973c4
DOI: 10.7287/peerj.preprints.2548v1

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