Article

Endoplasmic Reticulum Proteins Impact Penetrance in a <i>Pink1</i>-Mutant <i>Drosophila</i> Model

2024-12-19

Abstract excerpt

Parkinson’s disease (PD) is a neurodegenerative disorder with a high variability of age at onset, disease severity, and progression. This suggests that other factors, including genetic, environ-mental, or biological factors, are at play in PD. Loss of PINK1 causes a recessive form of PD and is typically fully penetrant; however, it features a wide range in disease onset, further supporting the existence of p...

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Literature Corpus work: 2355f5fc-b60d-58d1-9f3f-19f618a16c87
DOI: 10.20944/preprints202412.1641.v1

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