Article

Microsatellite Instability in Colorectal Cancer

2004-07-01

Abstract excerpt

In this review, we briefly outline the definitions of DNA microsatellites, microsatellite instability (MSI), and explain DNA mismatch repair. Methods for testing MSI are described and compared with the complementary approach of immunostaining for DNA mismatch repair proteins. The use of such testing is then presented with respect to hereditary nonpolyposis colorectal cancer (HNPCC) and sporadic colorectal cancer....

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9c60b6df-509b-5d39-95b3-bbf5ad4d5292
DOI: 10.1097/01.pcr.0000132991.85133.ef

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Microsatellite Instability in Colorectal CancerDOI 10.1097/01.pcr.0000132991.85133.efRead

Microsatellite instability in colorectal cancerSemantic proximity Read

DNA mismatch repair deficiency in sporadic colorectal cancer and Lynch syndromeSemantic proximity Read

MSI-testing in hereditary non-polyposis colorectal carcinoma (HNPCC).Semantic proximity Read

The clinical importance and prognostic implications of microsatellite instability in sporadic cancer.Semantic proximity Read

Differences between familial and sporadic forms of colorectal cancer with DNA microsatellite instability.Semantic proximity Read

Microsatellite instability in colorectal cancerSemantic proximity Read

Microsatellite instability in gastrointestinal tract cancers: a brief update.Semantic proximity Read

Molecular testing for microsatellite instability and DNA mismatch repair defects in hereditary and sporadic colorectal cancers--ready for prime time?Semantic proximity Read

Lynch Syndrome (HNPCC) and Microsatellite InstabilitySemantic proximity Read

Clinical Aspects of Microsatellite Instability Testing in Colorectal CancerSemantic proximity Read

Clinicopathologic features in colorectal cancer patients with microsatellite instability.Semantic proximity Read

Microsatellite instability in colorectal adenomas: relevance and clinical importance.Semantic proximity Read