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Article

Ribosome Profiling as a Tool to Decipher Viral Complexity

5 Aug 2015

Abstract excerpt

Viral genomes harbor a variety of unusual translational phenomena that allow them to pack coding information more densely and evade host restriction mechanisms imposed by the cellular translational apparatus. Annotating translated sequences within these genomes thus poses particular challenges, but identifying the full complement of proteins encoded by a virus is critical for understanding its life cycle and...

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PMID: 26958919
DOI: 10.1146/annurev-virology-100114-054854

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