Article
Identification of a cellular factor that modulates HIV-1 programmed ribosomal frameshifting.
The Journal of biological chemistry - 25 Jun 2010
Kobayashi Yoshifumi, Zhuang Jianling, Peltz Stuart, Dougherty Joseph
Abstract excerpt
Programmed -1 ribosomal frameshifting (PRF) is a distinctive mode of gene expression utilized by some viruses, including human immunodeficiency virus type 1 (HIV-1), to produce multiple proteins from a single mRNA. -1 PRF induces a subset of elongating ribosomes to shift their translational readi...
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