Article

Integrative computational approach identifies new targets in CD4+ T cell-mediated immune disorders

2020-01-02

Abstract excerpt

CD4+ T cells provide adaptive immunity against pathogens and abnormal cells, and they are also associated with various immune related diseases. CD4+ T cells’ metabolism is dysregulated in these pathologies and represents an opportunity for drug discovery and development. Genome-scale metabolic modeling offers an opportunity to accelerate drug discovery by providing high-quality information about possible target sp...

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Literature Corpus work: 9c2ff33f-1326-5c4f-a2db-b2f98dc30b1d
DOI: 10.1101/2020.01.02.893164

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