Article

Single Cell Sequencing Analysis Identifies Genetics-Modulated ORMDL3+ Cholangiocytes Having Higher Metabolic Effects On Primary Biliary Cholangitis

2021-09-24

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: Primary biliary cholangitis (PBC) is a classical autoimmune disease, which is highly influenced by genetic determinants. Many genome-wide association studies (GWAS) have reported that numerous genetic loci were significantly associated with PBC susceptibility. However, the effects of genetic determinants on liver cells and its immune microenvironment for PBC rem...

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Literature Corpus work: 1c8938c5-035a-5632-901a-b228d4d423e0
DOI: 10.21203/rs.3.rs-922624/v1

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