Article
The genetic architecture of quantitative traits.
Annual review of genetics - 1 Jan 2001
Mackay T F
Abstract excerpt
Phenotypic variation for quantitative traits results from the segregation of alleles at multiple quantitative trait loci (QTL) with effects that are sensitive to the genetic, sexual, and external environments. Major challenges for biology in the post-genome era are to map the molecular polymorphisms responsible for variation in medically, agriculturally, and evolutionarily important complex traits; and to...
Topics
- Animals
- Chromosome Mapping
- Genetic Linkage
- Genotype
- Humans
- Models, Genetic
- Mutation
- Polymorphism, Single Nucleotide
- Quantitative Trait, Heritable